Study of the mechanism of action of flax seed on functions of female gonads and uterus of animals
Basic information
Slovak title:
Štúdium mechanizmu účinku ľanového semena na funkcie samičích gonád a maternice zvierat
Registration No.:
1/0204/20
Source:
Scientific grant agency (Ministry of education, science, research and sport of the Slovak Republic)
Implementation time:
2020 - 2023
Principal (UVMP):
Vlčková Radoslava, doc. MVDr., PhD. (2020: 29.6% | 2021: 29.6% | 2022: 50% | 2023: 43.8%)
Principal workplace:
Department of Biology and Physiology
Principal workplace:
Department of Biology and Physiology
Contributors:
Sopková Drahomíra, doc. MVDr., PhD. (2020: 29.6% | 2021: 29.6% | 2022: 43.8% | 2023: 50%)
Petrilla Vladimír, MVDr., PhD. (2020: 3.8% | 2021: 3.8% | 2022: 6.2% | 2023: 6.2%)
Andrejčáková Zuzana, MVDr., PhD. (2020: 37% | 2021: 37% | 2022: 0% | 2023: 0%)
Field of study:
200 - Veterinary Sciences
Financial indicators
NON-CAPITAL FUNDING in €
CAPITAL FUNDING in €
Allocated
Spent
Allocated
Spent
Allocated / Spent
Allocated / Spent
2020
17940
16616.01
0
0
17940 / 16616.01
0 / 0
2021
18686
15075.80
0
0
18686 / 15075.80
0 / 0
2022
21511
20959.15
0
0
21511 / 20959.15
0 / 0
2023
13161
0
0
0
13161 / 0
0 / 0
Spolu
71298
52650.96
0
0
71298 / 52650.96
0 / 0
Anotation
Cieľom predkladaného projektu je preskúmať a objasniť vplyv ľanového semena na funkcie vaječníkov a
materníc rôznych druhov zvierat. Počas riešenia projektu budú v postupoch in vitro na kultivovaných bunkách
vaječníkov kobýl a ošípaných a v postupoch in vivo na štruktúrach vaječníkov ošípaných sledované zmeny v
expresii proliferačných a apoptotických markerov, rôznych receptorov, vo vylučovaní hormónov a rôznych
signálnych substancií a v ich odozve na nadriadené a lokálne regulátory. Budú sledované diferencie v zložení
folikulovej tekutiny a v štruktúre materníc, hustote a lokalizácii receptorov pre vybrané hormóny.
The aim of the present project is to investigate and clarify the effect of flax seed on ovarian and uterine functions
of various animal species. During the project, changes in the expression of proliferative and apoptotic markers,
several receptors, secretion of hormones and various signal substances and changes in their response to
superior and local regulators will be observed in in vitro experiments on cultured equine and porcine ovarian cells
and in vivo experiments on ovarian structures of gilts. Differences in composition of follicular fluid and in uterine
structure, density and localization of receptors for selected hormones will be observed.
Publication outputs
1
ADM
ANDREJČÁKOVÁ, Zuzana - VLČKOVÁ, Radoslava - SOPKOVÁ, Drahomíra - KOZIOŁ, Katarzyna - KOZIOROWSKI, Marek - FABIÁN, Dušan - ŠEFČÍKOVÁ, Zuzana - HOLOVSKÁ, Katarína - ALMÁŠIOVÁ, Viera - SIROTKIN, Alexander V.. Dietary flaxseed's protective effects on body tissues of mice after oral exposure to xylene. In: Saudi journal of biological sciences. 2021. ISSN 1319-562X, Vol. 28, no. 7 (2021), p. 3789-3798.
(2021: 4.052 - IF, 62 - H-index, 4.247 - IF 5y, 0.656 - SJR, Q1 - SJR Best Q, Q2 - JCR Best Q)
(2021: 4.052 - IF, 62 - H-index, 4.247 - IF 5y, 0.656 - SJR, Q1 - SJR Best Q, Q2 - JCR Best Q)