Design, synthesis, and evaluation of novel indole hybrid chalcones and their antiproliferative and antioxidant activity.

About the publication

Record:
KUDLIČKOVÁ, Zuzana - MICHALKOVÁ, Radka - SALAYOVÁ, Aneta - KSIAŽEK, Marián - VILKOVÁ, Mária - BEKEŠOVÁ, Slávka - MOJŽIŠ, Ján. Design, synthesis, and evaluation of novel indole hybrid chalcones and their antiproliferative and antioxidant activity. In: Molecules. 2023. ISSN 1420-3049, Vol. 28, no. 18 (2023), art. no. 6583, p. [1-21]
(2023: 4.200 - IF, 4.600 - IF 5y, 0.744 - SJR, Q1 - SJR Best Q, Q2 - JCR Best Q)
Year:
2023
Category:
V3 - Scientific output of publication activity from the journal
Output type:
CLA - article
Authors:
MICHALKOVÁ Radka
20 %
KSIAŽEK Marián
5 %
VILKOVÁ Mária
10 %
BEKEŠOVÁ Slávka
5 %
MOJŽIŠ Ján
10 %
UVMP share:
50 %
Edition:
Molecules
Vol. 28, no. 18 (2023), art. no. 6583, p. [1-21]
Country of issue:
Switzerland
ISSN:
1420-3049
Research area:
180 - Medical, pharmaceutical and non-medical health sciences
Field:
Group of study fields: Health sciences and fields aimed at improving the quality of life
Name of the field of study: pharmacy
Scientometrics:
2023: 4.200 - IF, 4.600 - IF 5y, 0.744 - SJR, Q1 - SJR Best Q, Q2 - JCR Best Q
Language:
english
 

Citations:

2025-2025: [1] ESTIASIH, Teti - WITOYO, Jatmiko Eko - WULANDARI, Khofifah Putri - JUNIATI, Fadhillah Dwi - SETYANINGSIH, Widiastuti - LIOE, Hanifah Nuryani - PALMA, Miguel - AHMADI, Kgs - RAY, Hamidie Ronald Daniel - MUFIDAH, Elya. Stability comparison of conventional and foam-mat red and purple dried roselle calyces powder as a function of pH. In AIMS Agriculture and Food, 2025-01-01, 10, 1, pp. 177-198. Dostupné na: https://doi.org/10.3934/AGRFOOD.2025010.
2025-2025: [1] ESTIASIH, Teti - WITOYO, Jatmiko Eko - WULANDARI, Khofifah Putri - JUNIATI, Fadhillah Dwi - SETYANINGSIH, Widiastuti - LIOE, Hanifah Nuryani - PALMA, Miguel - AHMADI, Kgs - RAY, Hamidie Ronald Daniel - MUFIDAH, Elya. Stability comparison of conventional and foam-mat red and purple dried roselle calyces powder as a function of pH. In AIMS Agriculture and Food, 2025-01-01, 10, 1, pp. 177-198. Dostupné na: https://doi.org/10.3934/AGRFOOD.2025010.
2025-2025: [1] IBRAHIM, Nada S. - SHOUKRY, Eman Hatem - SHARAKY, Marwa - DIAB, Hadeer M. - ELWAHY, Ahmed H.M. - ABDELHAMID, Ismail A. Synthesis, cytotoxicity, oxidative stress, anti-metastatic and anti-inflammatory effects of novel 2-methylene-1H-indene-1,3-dione tethered 2-(2-methoxyphenoxy)-N-arylacetamide: induction of apoptosis in HCT116 and HeLa cells. In Chemico-Biological Interactions, 2025-08-01, 416, pp. ISSN 00092797. Dostupné na: https://doi.org/10.1016/j.cbi.2025.111549.
2025-2025: [1] IBRAHIM, Nada S. - SHOUKRY, Eman Hatem - SHARAKY, Marwa - DIAB, Hadeer M. - ELWAHY, Ahmed H.M. - ABDELHAMID, Ismail A. Synthesis, cytotoxicity, oxidative stress, anti-metastatic and anti-inflammatory effects of novel 2-methylene-1H-indene-1,3-dione tethered 2-(2-methoxyphenoxy)-N-arylacetamide: induction of apoptosis in HCT116 and HeLa cells. In Chemico-Biological Interactions, 2025-08-01, 416, pp. ISSN 00092797. Dostupné na: https://doi.org/10.1016/j.cbi.2025.111549.
2025-2025: [1] RAJ, V. - CHANDOLA, A. - NAUTIYAL, U. - SEMWAL, A. - PANDEY, R. Chalcones: Beyond Bioactive Properties - Exploring Their Potential as Polymeric Materials. In JOURNAL OF POLYMER & COMPOSITES. ISSN 2321-8525, 2025, vol. 13. sp. iss., 997-1003.
2025-2025: [1] RAJ, V. - CHANDOLA, A. - NAUTIYAL, U. - SEMWAL, A. - PANDEY, R. Chalcones: Beyond Bioactive Properties - Exploring Their Potential as Polymeric Materials. In JOURNAL OF POLYMER & COMPOSITES. ISSN 2321-8525, 2025, vol. 13. sp. iss., 997-1003.
2025-2025: [1] TANYI, Solange A. - ENI, Donatus B. - ABDELSALAM, Mohamed - SCHMIDT, Matthias - SIPPL, Wolfgang - NTIE-KANG, Fidele. A Facile and Rapid Method for Synthesizing Indole–Chalcone Hybrids. In MolBank, 2025-03-01, 2025, 1, pp. Dostupné na: https://doi.org/10.3390/M1974.
2025-2025: [1] TANYI, Solange A. - ENI, Donatus B. - ABDELSALAM, Mohamed - SCHMIDT, Matthias - SIPPL, Wolfgang - NTIE-KANG, Fidele. A Facile and Rapid Method for Synthesizing Indole–Chalcone Hybrids. In MolBank, 2025-03-01, 2025, 1, pp. Dostupné na: https://doi.org/10.3390/M1974.
2025-2025: [1] UPPAL, Jasreen Kaur - SHARMA, Rajiv. Design, Synthesis, and Biological Evaluation of Triazole Tethered Coumarin-Indole Fused Chalcone-Isatin Derivatives as a New Class of Anti-Breast Cancer Agents. In Archiv Der Pharmazie, 2025-07-01, 358, 7, pp. ISSN 03656233. Dostupné na: https://doi.org/10.1002/ardp.70060.
2024-2024: [1] BATOOL, Zahra - ULLAH, Saeed - KHAN, Ajmal - MALI, Suraj N. - GURAV, Shailesh S. - JAWARKAR, Rahul D. - ALSHAMMARI, Abdulrahman - ALBEKAIRI, Norah A. - AL-HARRASI, Ahmed - SHAFIQ, Zahid. Design, synthesis, QSAR modelling and molecular dynamic simulations of N-tosyl-indole hybrid thiosemicarbazones as competitive tyrosinase inhibitors. In Scientific Reports, 2024-12-01, 14, 1, pp. Dostupné na: https://doi.org/10.1038/s41598-024-75100-1.
2024-2024: [1] BATOOL, Zahra - ULLAH, Saeed - KHAN, Ajmal - MALI, Suraj N. - GURAV, Shailesh S. - JAWARKAR, Rahul D. - ALSHAMMARI, Abdulrahman - ALBEKAIRI, Norah A. - AL-HARRASI, Ahmed - SHAFIQ, Zahid. Design, synthesis, QSAR modelling and molecular dynamic simulations of N-tosyl-indole hybrid thiosemicarbazones as competitive tyrosinase inhibitors. In Scientific Reports, 2024-12-01, 14, 1, pp. Dostupné na: https://doi.org/10.1038/s41598-024-75100-1.
2024-2024: [1] BATOOL, Zahra - ULLAH, Saeed - KHAN, Ajmal - SIDDIQUE, Farhan - NADEEM, Sumaira - ALSHAMMARI, Abdulrahman - ALBEKAIRI, Norah A. - TALIB, Rimsha - AL-HARRASI, Ahmed - SHAFIQ, Zahid. Design, synthesis, and in vitro and in silico study of 1-benzyl-indole hybrid thiosemicarbazones as competitive tyrosinase inhibitors. In RSC Advances, 2024-09-06, 14, 39, pp. 28524-28542. Dostupné na: https://doi.org/10.1039/d4ra05015k.
2024-2024: [1] BATOOL, Zahra - ULLAH, Saeed - KHAN, Ajmal - SIDDIQUE, Farhan - NADEEM, Sumaira - ALSHAMMARI, Abdulrahman - ALBEKAIRI, Norah A. - TALIB, Rimsha - AL-HARRASI, Ahmed - SHAFIQ, Zahid. Design, synthesis, and in vitro and in silico study of 1-benzyl-indole hybrid thiosemicarbazones as competitive tyrosinase inhibitors. In RSC Advances, 2024-09-06, 14, 39, pp. 28524-28542. Dostupné na: https://doi.org/10.1039/d4ra05015k.
2024-2024: [1] BATOOL, Zahra - ULLAH, Saeed - KHAN, Ajmal - SIDDIQUE, Farhan - NADEEM, Sumaira - ALSHAMMARI, Abdulrahman - ALBEKAIRI, Norah A. - TALIB, Rimsha - AL-HARRASI, Ahmed - SHAFIQ, Zahid. Design, synthesis, and in vitro and in silico study of 1-benzyl-indole hybrid thiosemicarbazones as competitive tyrosinase inhibitors. In RSC Advances, 2024-09-06, 14, 39, pp. 28524-28542. Dostupné na: https://doi.org/10.1039/d4ra05015k.
2024-2024: [1] CITARELLA, Andrea - VITTORIO, Serena - DANK, Christian - IELO, Laura. Syntheses, reactivity, and biological applications of coumarins. In Frontiers in Chemistry, 2024-01-01, 12, pp. Dostupné na: https://doi.org/10.3389/fchem.2024.1362992.
2024-2024: [1] CITARELLA, Andrea - VITTORIO, Serena - DANK, Christian - IELO, Laura. Syntheses, reactivity, and biological applications of coumarins. In Frontiers in Chemistry, 2024-01-01, 12, pp. Dostupné na: https://doi.org/10.3389/fchem.2024.1362992.
2024-2024: [1] IVANOVA, Yordanka B. - SVETOSLAVOV, Filip E. - PETROV, Ognyan I. (E)-5-(3-Oxo-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl)benzo[d]oxazol-2(3H)-one. In MolBank, 2024-09-01, 2024, 3, pp. Dostupné na: https://doi.org/10.3390/M1866.
2024-2024: [1] IVANOVA, Yordanka B. - SVETOSLAVOV, Filip E. - PETROV, Ognyan I. (E)-5-(3-Oxo-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl)benzo[d]oxazol-2(3H)-one. In MolBank, 2024-09-01, 2024, 3, pp. Dostupné na: https://doi.org/10.3390/M1866.
2024-2024: [1] MARINESCU, Maria. Bisindole Compounds—Synthesis and Medicinal Properties. In Antibiotics, 2024-12-01, 13, 12, pp. Dostupné na: https://doi.org/10.3390/antibiotics13121212.
2024-2024: [1] MARINESCU, Maria. Bisindole Compounds—Synthesis and Medicinal Properties. In Antibiotics, 2024-12-01, 13, 12, pp. Dostupné na: https://doi.org/10.3390/antibiotics13121212.
2024-2024: [1] OBIAD, Ehab Kareem - SALIM, Ahmed Thamer - RADHI, Ali Jabbar - MOHSEN, Tahseen Talib - KAHDUM, Bashaer Jawad. Green Synthesis, Molecular Docking Studies, and Antimicrobial Evaluation of Tetrazoles Derivatives. In Asian Journal of Green Chemistry, 2024-11-01, 8, 6, pp. 762-778. ISSN 25885839. Dostupné na: https://doi.org/10.48309/AJGC.2024.478818.1553.
2024-2024: [1] OBIAD, Ehab Kareem - SALIM, Ahmed Thamer - RADHI, Ali Jabbar - MOHSEN, Tahseen Talib - KAHDUM, Bashaer Jawad. Green Synthesis, Molecular Docking Studies, and Antimicrobial Evaluation of Tetrazoles Derivatives. In Asian Journal of Green Chemistry, 2024-11-01, 8, 6, pp. 762-778. ISSN 25885839. Dostupné na: https://doi.org/10.48309/AJGC.2024.478818.1553.
2024-2024: [1] XU, Yang - LIANG, Xuhui - HYUN, Chang Gu. Discovery of Indole–Thiourea Derivatives as Tyrosinase Inhibitors: Synthesis, Biological Evaluation, Kinetic Studies, and In Silico Analysis. In International Journal of Molecular Sciences, 2024-09-01, 25, 17, pp. ISSN 16616596. Dostupné na: https://doi.org/10.3390/ijms25179636.
2024-2024: [1] XU, Yang - LIANG, Xuhui - HYUN, Chang Gu. Discovery of Indole–Thiourea Derivatives as Tyrosinase Inhibitors: Synthesis, Biological Evaluation, Kinetic Studies, and In Silico Analysis. In International Journal of Molecular Sciences, 2024-09-01, 25, 17, pp. ISSN 16616596. Dostupné na: https://doi.org/10.3390/ijms25179636.
2024-2024: [1] XU, Yang - LIANG, Xuhui - HYUN, Chang Gu. Discovery of Indole–Thiourea Derivatives as Tyrosinase Inhibitors: Synthesis, Biological Evaluation, Kinetic Studies, and In Silico Analysis. In International Journal of Molecular Sciences, 2024-09-01, 25, 17, pp. ISSN 16616596. Dostupné na: https://doi.org/10.3390/ijms25179636.
2023-2023: [1] KUZOVLEV, Andrey S. - ZYBALOV, Mikhail D. - GOLOVIN, Andrey V. - GUREEV, Maxim A. - KASATKINA, Mariia A. - BIRYUKOV, Mikhail V. - BELIK, Albina R. - SILONOV, Sergey A. - YUNIN, Maxim A. - ZIGANGIROVA, Nailya A. - RESHETNIKOV, Vasiliy V. - ISAKOVA, Yulia E. - POROZOV, Yuri B. - IVANOV, Roman A. Naphthyl-Substituted Indole and Pyrrole Carboxylic Acids as Effective Antibiotic Potentiators—Inhibitors of Bacterial Cystathionine γ-Lyase. In International Journal of Molecular Sciences, 2023-11-01, 24, 22, pp. ISSN 16616596. Dostupné na: https://doi.org/10.3390/ijms242216331.
2023-2023: [1] KUZOVLEV, Andrey S. - ZYBALOV, Mikhail D. - GOLOVIN, Andrey V. - GUREEV, Maxim A. - KASATKINA, Mariia A. - BIRYUKOV, Mikhail V. - BELIK, Albina R. - SILONOV, Sergey A. - YUNIN, Maxim A. - ZIGANGIROVA, Nailya A. - RESHETNIKOV, Vasiliy V. - ISAKOVA, Yulia E. - POROZOV, Yuri B. - IVANOV, Roman A. Naphthyl-Substituted Indole and Pyrrole Carboxylic Acids as Effective Antibiotic Potentiators—Inhibitors of Bacterial Cystathionine γ-Lyase. In International Journal of Molecular Sciences, 2023-11-01, 24, 22, pp. ISSN 16616596. Dostupné na: https://doi.org/10.3390/ijms242216331.
2023-2023: [1] LU, Li - HU, Chunmei - MIN, Xiaofeng - LIU, Zhong - XU, Xuetao - GAN, Lishe. In Vitro and In Vivo Biological Evaluation of Indole-thiazolidine-2,4-dione Derivatives as Tyrosinase Inhibitors. In Molecules, 2023-11-01, 28, 22, pp. Dostupné na: https://doi.org/10.3390/molecules28227470.
2023-2023: [1] LU, Li - HU, Chunmei - MIN, Xiaofeng - LIU, Zhong - XU, Xuetao - GAN, Lishe. In Vitro and In Vivo Biological Evaluation of Indole-thiazolidine-2,4-dione Derivatives as Tyrosinase Inhibitors. In Molecules, 2023-11-01, 28, 22, pp. Dostupné na: https://doi.org/10.3390/molecules28227470.
2023-2023: [1] MENDOGRALO, Elena Y. - NESTEROVA, Larisa Y. - NASIBULLINA, Ekaterina R. - SHCHERBAKOV, Roman O. - MYASNIKOV, Danil A. - TKACHENKO, Alexander G. - SIDOROV, Roman Y. - UCHUSKIN, Maxim G. Synthesis, Antimicrobial and Antibiofilm Activities, and Molecular Docking Investigations of 2-(1H-Indol-3-yl)-1H-benzo[d]imidazole Derivatives. In Molecules, 2023-10-01, 28, 20, pp. Dostupné na: https://doi.org/10.3390/molecules28207095.
2023-2023: [1] MENDOGRALO, Elena Y. - NESTEROVA, Larisa Y. - NASIBULLINA, Ekaterina R. - SHCHERBAKOV, Roman O. - MYASNIKOV, Danil A. - TKACHENKO, Alexander G. - SIDOROV, Roman Y. - UCHUSKIN, Maxim G. Synthesis, Antimicrobial and Antibiofilm Activities, and Molecular Docking Investigations of 2-(1H-Indol-3-yl)-1H-benzo[d]imidazole Derivatives. In Molecules, 2023-10-01, 28, 20, pp. Dostupné na: https://doi.org/10.3390/molecules28207095.