Inhibition of furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities.
About the publication
Record:
ZIANE-CHAOUCHE, Lydia - RAFFO-ROMERO, Antonella - HAJJAJI, Nawale - KOBEISSY, Firas - PINHEIRO, Donna - ABOULOUARD, Soulaimane - COZZANI, Adeline - MITRA, Suman - FOURNIER, Isabelle - ČÍŽKOVÁ, Dáša - SALZET, Michel - DUHAMEL, Marie. Inhibition of furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities. In: Cell death and disease. 2024. ISSN 2041-4889, Vol. 15, no. 12 (2024), art. no. 879, p. [1-16]
(2024: 9.600 - IF, 181 - H-index, 9.800 - IF 5y, 2.773 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q)
(2024: 9.600 - IF, 181 - H-index, 9.800 - IF 5y, 2.773 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q)
Year:
2024
Category:
V3 - Scientific output of publication activity from the journal
Output type:
CLA - article
Authors:
ZIANE-CHAOUCHE Lydia
16 %
RAFFO-ROMERO Antonella
7 %
HAJJAJI Nawale
7 %
KOBEISSY Firas
5 %
PINHEIRO Donna
5 %
ABOULOUARD Soulaimane
6 %
COZZANI Adeline
5 %
MITRA Suman
5 %
FOURNIER Isabelle
7 %
7 %
SALZET Michel
15 %
DUHAMEL Marie
15 %
UVMP share:
7 %
Edition:
Cell death and disease
Vol. 15, no. 12 (2024), art. no. 879, p. [1-16]
Country of issue:
United Kingdom
ISSN:
2041-4889
Research area:
200 - Veterinary Sciences
Field:
Group of study fields: Agricultural and veterinary sciences
Name of the field of study: veterinary medicine
Scientometrics:
2024: 9.600 - IF, 181 - H-index, 9.800 - IF 5y, 2.773 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q
Language:
english
Citations:
1. 2026: [1] BAYAT, Mobina - NAHAND, Javid Sadri. CAR-engineered cell therapies: current understandings and future perspectives. In MOLECULAR BIOMEDICINE, 2026, vol. 7, no. 1, pp. Dostupné na: https://doi.org/10.1186/s43556-025-00401-4.
2. 2026: [1] CHEN, Yizhao - ZHOU, Lucheng - CHEN, Xinlei - WANG, Shuai - CHEN, Weiwei - LI, Zixuan - QIU, Ji - LI, Ruilin - TU, Jiajie - LIN, Ning. Optimizing next-generation CAR-macrophages against solid tumors: challenges and potential strategies. In JOURNAL OF HEMATOLOGY & ONCOLOGY. ISSN 1756-8722, 2026, vol. 19, no. 1, art. no. 30. pp. Dostupné na: https://doi.org/10.1186/s13045-026-01792-9.
3. 2026: [1] FU, Zhipeng - ZHAO, Xiaotian - ZHANG, Qikang - HAN, Maosen - ZHANG, Jing - YANG, Zhenmei - WANG, Yan - YAO, Zichao - LIU, Ying - TANG, Chunwei - XI, Kaiyan - LIU, Zhanyan - ZHANG, Yi - ZHAO, Kun - LI, Na - ZHANG, Yulin - SONG, Yudong - JIANG, Xinyi - CHEN, Chen. Synthetic SIGLEC9-based chimeric switch receptor augments the efficacy of CAR macrophages against glioblastoma. In PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Vol. 123, no. 12 (2026), pp. Dostupné na: https://doi.org/10.1073/pnas.2519819123. ISSN 0027-8424.
4. 2026: [1] JASSAUD, Marius - ZIANE-CHAOUCHE, Lydia - DUHAMEL, Marie - SALZET, Michel. Innate immune cells in chimeric antigen receptor therapy. In MOLECULAR THERAPY. Vol. 34, no. 1 (2026), pp. 97-116. Dostupné na: https://doi.org/10.1016/j.ymthe.2025.10.003. ISSN 1525-0016.
5. 2026: [1] LI, Xinyang - LIU, Chong - HU, Haidi. The expanding role of Furin in human Disease: A comprehensive review. In GENE. Vol. 981, no. (2026), pp.. Dostupné na: https://doi.org/10.1016/j.gene.2025.149969. ISSN 0378-1119.
6. 2026: [1] NARDO, Giuseppe - PUTTI, Francesca - INDINI, Alice - DEL VECCHIO, Michele - DE BRAUD, Filippo - DI NICOLA, Massimo - DE SANTIS, Francesca. CAR-engineering of innate and innate-like immune cells: a new horizon in adoptive cell therapy for solid tumors. In JOURNAL FOR IMMUNOTHERAPY OF CANCER. Vol. 14, no. 5 (2026), pp.. Dostupné na: https://doi.org/10.1136/jitc-2025-014592.
7. 2026: [1] NARDO, Giuseppe - PUTTI, Francesca - INDINI, Alice - DEL VECCHIO, Michele - DE BRAUD, Filippo - DI NICOLA, Massimo - DE SANTIS, Francesca. CAR-engineering of innate and innate-like immune cells: a new horizon in adoptive cell therapy for solid tumors.. JOURNAL FOR IMMUNOTHERAPY OF CANCER. Vol. 14, no. 5 (2026), pp. Dostupné na: https://doi.org/10.1136/jitc-2025-014592.
8. 2026: [1] PAN, Junjie - CHEN, Shixin - JIN, Lingxiao - CHEN, Keye - YE, Zhaoming - LI, Binghao. Immunotherapy-driven remodeling of the tumor immune microenvironment: Spatiotemporal heterogeneity and multidimensional dynamics. In BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. Vol. 1881, no. 2 (2026), pp. Dostupné na: https://doi.org/10.1016/j.bbcan.2026.189544. ISSN 0304-419X.
9. 2026: [1] SIEGFRIED, Geraldine - LIU, Yiyang - HE, Zongcheng - EVRARD, Serge - BADIOLA, Iker - PERNOT, Simon - CREEMERS, John W. M. - KHATIB, Abdel-Majid. Furin-like enzyme dependency in KRAS-mutant colorectal cancer as a target for personalized treatment strategies. In BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2026, vol. 1881, no. 4, pp. ISSN 0304-419X. Dostupné na: https://doi.org/10.1016/j.bbcan.2026.189620.
10. 2025: [1] DING, Xin - ZHANG, Yang - CHU, Songshen - HUANG, Song - WANG, Jiajia - LI, Xia. Enhancement of Targeted and Antitumor Effects of M1 Macrophages Based on Bioorthogonal Reactions. In MOLECULAR PHARMACEUTICS, 2025, vol. 22, no. 10, pp. 6151-6162. ISSN 1543-8384. Dostupné na: https://doi.org/10.1021/acs.molpharmaceut.5c00856.
11. 2025: [1] DING, Xin - ZHANG, Yang - CHU, Songshen - HUANG, Song - WANG, Jiajia - LI, Xia. Enhancement of Targeted and Antitumor Effects of M1 Macrophages Based on Bioorthogonal Reactions. In MOLECULAR PHARMACEUTICS, 2025, vol. 22, no. 10, pp. 6151-6162. ISSN 1543-8384. Dostupné na: https://doi.org/10.1021/acs.molpharmaceut.5c00856.
12. 2025: [1] IBRAHIM, Abdulrahman - LIANG, Zihao - LIU, Wan - DI, Xiaofei - RABIU, Lawan - LI, Rong - ZHANG, Pengchao - SALIU, Muhammad Auwal - LIU, Maoxuan - ZHANG, Guizhong - WAN, Xiaochun - YAN, Dehong. CD86 costimulation enhances the antitumor activity of NKG2D CAR-Macrophages and synergizes with Anti-PD-L1 therapy to suppress prostate cancer progression. In CELL COMMUNICATION AND SIGNALING, 2025, vol. 23, no. 1, pp. Dostupné na: https://doi.org/10.1186/s12964-025-02548-7.
13. 2025: [1] IBRAHIM, Abdulrahman - LIANG, Zihao - LIU, Wan - DI, Xiaofei - RABIU, Lawan - LI, Rong - ZHANG, Pengchao - SALIU, Muhammad Auwal - LIU, Maoxuan - ZHANG, Guizhong - WAN, Xiaochun - YAN, Dehong. CD86 costimulation enhances the antitumor activity of NKG2D CAR-Macrophages and synergizes with Anti-PD-L1 therapy to suppress prostate cancer progression. In CELL COMMUNICATION AND SIGNALING, 2025, vol. 23, no. 1, pp. Dostupné na: https://doi.org/10.1186/s12964-025-02548-7.
14. 2025: [1] JI, Yanan - LI, Xia - YAO, Xinlei - SUN, Jiacheng - YI, Jia - SHEN, Yuntian - CHEN, Bingqian - SUN, Hualin. Macrophage polarization: molecular mechanisms, disease implications, and targeted therapeutic strategies. In FRONTIERS IN IMMUNOLOGY, 2025, vol. 16, no., pp. ISSN 1664-3224. Dostupné na: https://doi.org/10.3389/fimmu.2025.1732718.
15. 2025: [1] JI, Yanan - LI, Xia - YAO, Xinlei - SUN, Jiacheng - YI, Jia - SHEN, Yuntian - CHEN, Bingqian - SUN, Hualin. Macrophage polarization: molecular mechanisms, disease implications, and targeted therapeutic strategies. In FRONTIERS IN IMMUNOLOGY, 2025, vol. 16, no., pp. ISSN 1664-3224. Dostupné na: https://doi.org/10.3389/fimmu.2025.1732718.
16. 2025: [1] MORVA, Ahsen - ARROYO, Ana Belén - ANDREEVA, Liudmila - TAPIA-ABELLÁN, Ana - LUENGO-GIL, Ginés. Unleashing the power of CAR-M therapy in solid tumors: a comprehensive review. In Frontiers in Immunology, 2025-01-01, 16, pp. Dostupné na: https://doi.org/10.3389/fimmu.2025.1615760.
17. 2025: [1] SUUR, Bianca E. - KARADIMOU, Glykeria - WILLEMS, Colin J.J.M. - BERGMAN, Otto - LENGQUIST, Mariette - KRONQVIST, Malin - BAUMGARTNER, Roland - MALIN, Stephen - GISTERÅ, Anton - HANSSON, Göran K. - MÄLARSTIG, Anders - HEDIN, Ulf - KETELHUTH, Daniel F.J. - MATIC, Ljubica. PCSK6 ablation in blood circulating cells increases atherosclerotic burden, but improves plaque stability by activating Th17-smooth muscle cell modulatory axis. In Vascular Pharmacology, 2025-06-01, 159, pp. ISSN 15371891. Dostupné na: https://doi.org/10.1016/j.vph.2025.107490.
18. 2025: [1] WANG, Mengru - QIN, Zhen - BIAN, Xiu-Wu - SHI, Yu. Harnessing chimeric antigen receptor macrophages against solid tumors. In CANCER COMMUNICATIONS, 2025, vol. 45, no. 11, pp. 1344-1366. Dostupné na: https://doi.org/10.1002/cac2.70053.
19. 2025: [1] WANG, Mengru - QIN, Zhen - BIAN, Xiu-Wu - SHI, Yu. Harnessing chimeric antigen receptor macrophages against solid tumors. In CANCER COMMUNICATIONS, 2025, vol. 45, no. 11, pp. 1344-1366. Dostupné na: https://doi.org/10.1002/cac2.70053.
20. 2025: [1] WEI, Daoyan - WANG, Liang - LIU, Yi - ZUO, Xiangsheng - SHEN, Xiling - BRESALIER, Robert S. CAR-Macrophage Cell Therapy: A New Era of Hope for Pancreatic Cancer. In CLINICAL CANCER RESEARCH, 2025, vol. 31, no. 19, pp. 4018-4031. ISSN 1078-0432. Dostupné na: https://doi.org/10.1158/1078-0432.CCR-25-1201.
21. 2025: [1] WEI, Daoyan - WANG, Liang - LIU, Yi - ZUO, Xiangsheng - SHEN, Xiling - BRESALIER, Robert S. CAR-Macrophage Cell Therapy: A New Era of Hope for Pancreatic Cancer. In CLINICAL CANCER RESEARCH, 2025, vol. 31, no. 19, pp. 4018-4031. ISSN 1078-0432. Dostupné na: https://doi.org/10.1158/1078-0432.CCR-25-1201.